Isotopically Labeled Compounds
Medchemexpress LLC Macitentan-d4 | 1258428-05-5 | 98.0% | 592.30 | C19H16D4Br2N6O4S | 5 MG
Macitentan-d4 is a deuterium-labeled analogue of macitentan provided as an isotope-labeled reference standard for analytical and research applications, particularly as an internal standard for LC-MS or GC-MS quantification and method development.
- High isotopic labeling for accurate mass spectrometry quantification.
- Analytical-grade purity suitable for reference standards.
- Small pack size convenient for assay development and validation.
- Documented chemical and molecular data for traceability.
- Stable when stored per recommended conditions.
Medchemexpress LLC Acetophenone-d8 | 19547-00-3 | MFCD00064447 | 100.0% | 128.20 g·mol⁻¹ | C8D8O | 5g
Acetophenone-d8 is the deuterium labeled Acetophenone Acetophenone is an organic compound with simple structure[1]
Medchemexpress LLC Cariprazine-d8 | 1308278-50-3 | 98.77% | 435.46 | 5 MG
Cariprazine-d8 is a deuterium labeled Cariprazine. Cariprazine is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Targets D3 and 5-HT1A receptors.
Medchemexpress LLC Aldicarb (sulfone) | 1646-88-4 | 99.46% | 222.26 | 50 MG
Aldicarb sulfone is a metabolite of the carbamate pesticide Aldicarb, exhibiting insecticidal activity. It is also known to be a cholinesterase inhibitor.
- Inhibits egg hatching in *Tylenchulus semipenetrans*
- Reduces nematode motility
- Hindered male larval development
- Decreased plasma pseudocholinesterase levels in rats
- Decreased red blood cell cholinesterase levels in rats
Medchemexpress LLC Banoxantrone-d12 dihydrochloride | 1562066-98-1 | 95.0% | C22H18D12Cl2N4O6 | 10MG
Banoxantrone-d12 dihydrochloride is the deuterium-labeled form of the bioreductive prodrug banoxantrone (AQ4N), supplied as a solid dihydrochloride for research use. It is intended for isotope tracing, mass-shift experiments, metabolic stability, and pharmacokinetic studies, and is provided with ~95% purity (CAS 1562066-98-1).
- Deuterium-labeled for isotope tracing and mass-shift experiments.
- Suitable for metabolic stability and pharmacokinetic studies.
- High purity for reliable analytical and mass spectrometry results.
- Solid dihydrochloride form for convenient handling and storage.
- Well characterized with molecular formula C22H18D12Cl2N4O6 for unambiguous identification.
Medchemexpress LLC Flumatinib-d3 | >98% | 565.61 | 1 MG
Flumatinib-d3 is deuterium labeled Flumatinib. Flumatinib (HHGV678) is an orally available, selective inhibitor of Bcr-Abl. Flumatinib inhibits c-Abl, PDGFRβ, and c-Kit with IC50s of 1.2 nM, 307.6 nM, and 665.5 nM, respectively.
- Deuterium labeled Flumatinib
- Orally available
- Selective inhibitor of Bcr-Abl
- Inhibits c-Abl with IC50 of 1.2 nM
- Inhibits PDGFRβ with IC50 of 307.6 nM
- Inhibits c-Kit with IC50 of 665.5 nM
Medchemexpress LLC Glutaric acid-d4 | 19136-99-3 | 99.5% | 136.14 | 25 MG
Glutaric acid-d4 is a deuterium-labeled form of Glutaric acid. Glutaric acid is a C5 dicarboxylic acid that plays a role as an intermediate in the catabolic pathways of lysine and tryptophan. It has been observed to influence pericyte contractility and migration. Additionally, Glutaric acid is recognized as an indicator for glutaric aciduria type I. This product is intended for research use only.
- Used as a tracer in research applications.
- Suitable as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Heavy isotopes like deuterium can impact the pharmacokinetic and metabolic profiles of pharmaceutical compounds.
Medchemexpress LLC (±)12(13)Epoxy-9Z-octadecenoic-9,10,12,13-d4 acid | 17966-13-1 | 99.0% | 300.47 | 25 UG
(±)12(13)-EpOME-d4 is a deuterium labeled compound designed for research use. It can serve as a tracer and an internal standard in quantitative analysis methods such as NMR, GC-MS, or LC-MS. Deuteration may influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis
- Applicable in NMR, GC-MS, or LC-MS
- Deuterium labeled compound
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Revvity Health Sciences Inc dCTP, [α-32P]- 3000Ci/mmol 10mCi/ml EasyTide, 1 mCi
dCTP, [α-32P]- 3000Ci/mmol 10mCi/ml EasyTide, 1 mCi
Medchemexpress LLC Uridine-13C,15N2 | 369656-75-7 | 1 MG
Uridine-13C,15N2 is a 13C- and 15N-labeled Uridine. It is intended for research use only. This compound can be used as a tracer and as an internal standard for quantitative analysis. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules as tracers for quantitation during drug development. Deuteration has gained attention due to its potential to affect pharmacokinetic and metabolic profiles of drugs.
- Can be utilized as a tracer.
- Serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
Medchemexpress LLC Valproic acid-d6 | 87745-18-4 | MFCD01074058 | 99.8% | 150.25 g/mol | C8H10D6O2 | 1 MG
Valproic acid-d6 is the deuterium-labeled analogue of valproic acid used as an isotopic standard and tracer in analytical and research workflows. It provides a defined mass shift for accurate quantitation by mass spectrometry and is supplied as a high-purity reagent in small-scale quantities.
- Deuterium-labeled analogue for use as an internal standard in mass spectrometry.
- High purity suitable for analytical applications (reported 99.8%).
- Molecular formula C8H10D6O2; molecular weight 150.25 g/mol.
- Supplied as a small, 1 mg package for method development and validation.
- Store at -20°C for long-term stability; short-term storage at 4°C.
Medchemexpress LLC Pirfenidone-d5 | 1020719-62-3 | MFCD07369537 | 98.9% | 190.25 g/mol | C12H6D5NO | 10 MG
Pirfenidone-d5 is the deuterium-labeled isotopologue of pirfenidone used as an analytical reference and internal standard in quantitative mass spectrometry and pharmacokinetic studies. It provides a chemically similar labeled compound for accurate quantitation of pirfenidone in biological and biochemical assays.
- Deuterium-labeled internal standard for LC-MS/MS assays
- High purity (~98.9%) suitable for analytical use
- Molecular weight 190.25 g/mol; formula C12H6D5NO
- Available as a 10 mg vial for laboratory use
- Suitable for pharmacokinetic and metabolic studies
Cambridge Isotope Laboratories DL-Cotinine (2 3 4-13C3 99%) 100 ug/mL in water 1 2 mL
DL-Cotinine (2 3 4-13C3 99%) 100 ug/mL in water 1 2 mL
Medchemexpress LLC Cabozantinib-d6 | 1802168-46-2 | 98.14% | 507.54 | 5 MG
Cabozantinib-d6 is the deuterium labeled form of Cabozantinib, a potent inhibitor of multiple receptor tyrosine kinases (RTKs). It is suitable for use as a tracer or as an internal standard for quantitative analysis in various analytical methods.
- Inhibits VEGFR2, c-Met, Kit, Axl, and Flt3.
- Used as a tracer for quantitation during the drug development process.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs.
- For research use only and not for medical applications.
- Store at 4°C, protected from light.